Accès ouvert
2025
conference-abstract
OpenAlex
Ava Kominski, Jana Sefcikova, Jasmine Elsayed, Tamika LaRose et autres
DNA damage can disrupt cellular DNA replication mechanisms leading to increased mutagenesis, a hallmark of cancer. Based on homology models, Pol A2, a DNA polymerase protein from the bacterium Rothia dentocariosa, appears to play a role in the DNA damage response by …
mx
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Kathryn C. Asalone, Kara Ryan, Maryam Yamadi, Annastelle Cohen et autres
High levels of heterozygosity present a unique genome assembly challenge and can adversely impact downstream analyses, yet is common in sequencing datasets obtained from non-model organisms. Here we show that by re-assembling a heterozygous dataset with variant parameters and different assembly algorithms, …
us
(code pays fourni par la source)
Accès ouvert
2020
dataset
OpenAlex
Kathryn C. Asalone, Kara Ryan, Maryam Yamadi, Annastelle Cohen et autres
Alternate genome assemblies were generated using Illumina data from a published study (Weinstein et al, 2019) publicly available on Sequence Reads Archive (SRA) at accession PRJNA528747. Assemblies were generated with either Platanus or SoapDenovo2 using varying step-sizes (Platanus) or kmers (SoapDenovo2) and …
us
(code pays fourni par la source)
Accès ouvert
2020
dataset
OpenAlex
Kathryn C. Asalone, Kara Ryan, Maryam Yamadi, Annastelle Cohen et autres
Alternate genome assemblies were generated using Illumina data from a published study (Weinstein et al, 2019) publicly available on Sequence Reads Archive (SRA) at accession PRJNA528747. Assemblies were generated with either Platanus or SoapDenovo2 using varying step-sizes (Platanus) or kmers (SoapDenovo2) and …
us
(code pays fourni par la source)