Massimo Napodano

Right ventricular-pulmonary artery uncoupling identifies higher risk of combined pulmonary hypertension in patients undergoing TAVR

Francesco Putortì, Tommaso Fabris, Consolato Mesiani, Simone Tripi et autres

INTRODUCTION: Right ventricular-pulmonary artery (RV-PA) uncoupling, expressed as the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure (TAPSE/PAPs) ratio, is a negative prognostic indicator in patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS). This study aims to investigate …

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Measured Versus Predicted Prosthesis–Patient Mismatch after TAVR in Sievers Type 1 BAV: Incidence, Determinants, and Outcomes From the AD-HOC Registry

Tommaso Fabris, Federico Arturi, Andrea Buono, Chiara de Biase et autres

BACKGROUND: Evidence regarding prosthesis–patient mismatch (PPM), measured (mPPM), and predicted (pPPM), after transcatheter aortic valve replacement in bicuspid aortic valve stenosis remains limited. This study sought to evaluate the incidence, predictors, and prognostic implications of mPPM and pPPM in patients with Sievers …

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Emergency Transcatheter Edge-to-Edge Mitral Valve Repair as a Bail-Out Strategy After Failed NeoChord Surgical Repair in Acute Degenerative Mitral Regurgitation

Marco Putti, Giulia Masiero, Chiara Fraccaro, Tommaso Fabris et autres

Relevant mitral regurgitation (MR) is associated with significant morbidity and mortality. Surgical mitral valve (MV) repair represents the treatment of choice for symptomatic severe degenerative mitral regurgitation (DMR) in patients with acceptable surgical risk. However, surgical failure and high perioperative risk may …

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Biopsy-proven myocarditis: peripheral immunophenotypes correlate with histology, etiology, immunosuppressive therapy

Cristina Vicenzetto, Andrea Silvio Giordani, Anna Baritussio, Federico Scognamiglio et autres

Myocarditis is an inflammatory disease of the myocardium with infectious or immune-mediated/autoimmune etiology; etiology diagnosis relays on endomyocardial biopsy (EMB). High titre serum anti-heart autoantibodies (AHA) define severe autoimmune forms. In autoimmune myocarditis immunosuppression (IS) may be required to prevent progression to …

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Rescuing a Popped-Up Prosthesis

Consolato Mesiani, Tommaso Fabris, Francesco Putortì, Michele Strosio et autres

OBJECTIVE: We report the successful management of a 30-mm Hydra self-expanding tall-frame transcatheter heart valve (THV) pop-up through a redo TAVI procedure. KEY STEPS: A new Safari extra-stiff guidewire was advanced externally in respect of a 30-mm Hydra valve frame. A 25-mm …

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Management of anaesthesia for transfemoral transcatheter aortic valve implantation: an Italian interdisciplinary consensus statement

Valentina Ajello, Stefano Fresilli, Filippo D’Amico, Giulia Franceschini et autres

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Physiology vs angiography-guided percutaneous coronary intervention in transcatheter aortic valve implantation: the FAITAVI trial

Flavio Luciano Ribichini, Roberto Scarsini, Gabriele Pesarini, Tommaso Fabris et autres

BACKGROUND AND AIMS: The optimal approach to coronary revascularization in patients undergoing transcatheter aortic valve implantation (TAVI) remains debated. Fractional flow reserve (FFR) may improve the identification of ischaemia-producing lesions compared to angiographic assessment alone, but data in the TAVI population are …

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Multifactorial Predisposition in Biopsy-Proven Autoimmune and Viral Myocarditis

Alida L.P. Caforio, Maria Bueno Marinas, Andrea Silvio Giordani, Rudy Celeghin et autres

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Unmasking Myocardial Bridge–Related Ischemia by Quantitative Flow Ratio Functional Evaluation

Francesco Cardaioli, Tommaso Sciarretta, Federico Arturi, Tommaso Fabris et autres

A myocardial bridge (MB) is a condition where a segment of an epicardial coronary artery passes through the myocardial muscle. While traditionally regarded as benign, MBs have been associated with various cardiovascular conditions. Therefore, assessing their hemodynamic impact is crucial for informed …

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Computed Tomography Scan Predictors and Prognostic Impact of Combined Pulmonary Hypertension in Patients With Aortic Valve Stenosis undergoing TAVI

Francesco Putortì, Tommaso Fabris, Michele Strosio, Consolato Mesiani et autres

Precapillary (PrPH) and combined pre and postcapillary pulmonary hypertension (CoPH) increase all-cause and cardiovascular mortality risk in patients undergoing TAVI for severe symptomatic aortic stenosis. Since pulmonary artery (PA) diameter adapts to increased pulmonary artery pressure, this study evaluates the correlation between …

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Impact of Updated Invasive Right Ventricular and Pulmonary Hemodynamics on Long-Term Outcomes in Patients With Mitral Valve Transcatheter Edge-to-Edge Repair

Giulia Masiero, Federico Arturi, Elisa Boscolo Soramio, Luca Nai Fovino et autres

Right-sided cardiac catheterization (RHC) is selectively recommended in mitral valve transcatheter edge-to-edge (M-TEER) workup because right ventricle (RV) hemodynamic parameters predict adverse outcomes. This study examines the impact of RV hemodynamics and the prognostic value of the 2022 European Society of Cardiology …

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Long-term survival after TAVI in low-flow, low-gradient aortic valve stenosis

Francesco Cardaioli, Luca Nai Fovino, Tommaso Fabris, Giulia Masiero et autres

BACKGROUND: In patients undergoing transcatheter aortic valve implantation (TAVI), the presence of a low-flow, low-gradient (LFLG) status has been associated with higher mortality at short-term follow-up. AIMS: We aimed to evaluate long-term survival after TAVI in patients with classical (cLFLG) and paradoxical …

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