HoonSung Jeh

Abstract LB075: Development of SARS-CoV-2 neutralizing protein by ACE2 receptor engineering for severe infection and patients with underlying diseases

Byoung Se Kwon, Seunghyun Lee, Jin-Kyung Choi, Bora Hwang et autres

Abstract Since the Spike protein on the surface of SARS coronavirus 2 (SARS-CoV-2) binds to the ACE2 receptor in human cells, the development of neutralizing proteins or antibodies targeting the receptor binding domain (RBD) of the spike protein is an important strategy …

kr (code pays fourni par la source)

Abstract LB176: Anti-4-1BB x PD-1, a bispecific anti-cancer therapeutics

Byoung S. Kwon, Hanna Lee, Jin‐Sung Park, Yeonji Oh et autres

Abstract 4-1BB and PD-1 are both T cell costimulatory receptors/immune checkpoint regulators. 4-1BB/4-1BBL provides stimulatory signals while PD-1/PD-L1, suppressive ones to T lymphocytes. Various forms of agonists to 4-1BB or blockers to PD-1 have shown a potent anti-cancer activity by modulating mainly …

Development of SARS-CoV-2 neutralizing protein by ACE2 receptor engineering for severe infection and patients with underlying diseases

B. S. Kwon, Seung Jae Lee, Jihyang Choi, Beom Jeung Hwang et autres