Accès ouvert
2026
other
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
DDR mutations. A, Mutation landscape of the 20 most frequently mutated DDR genes in baseline ctDNA. Kaplan–Meier plots for OS by (B) KEGG DDR mutation status and treatment arm, (C) KEGG DDR and TP53 mutation status with SG, (D) KEGG DDR and …
Accès ouvert
2026
other
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Potential resistance mutations. A,TP53, STK11, and KEAP1 mutation and KRAS driver alteration landscape. B,TP53, STK11, and KEAP1 mutation status relative frequency by best response to last prior anti–PD-(L)1–containing therapy and treatment arm. Kaplan–Meier plots for OS by treatment arm and (C) TP53, …
Accès ouvert
2026
other
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Abstract Purpose: This exploratory analysis assessed predictive biomarkers for sacituzumab govitecan (SG) in the open-label, phase III EVOKE-01 study of SG versus docetaxel in non–small cell lung cancer (NSCLC). Patients and Methods: Trophoblast cell-surface antigen (Trop) 2 membrane protein expression was analyzed …
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Response rates by treatment arm and Trop-2 median H-score subgroup in the Trop-2 biomarker evaluable population.
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
DDR pathway forest plot analysis, adjusted for TP53.
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Kaplan-Meier plots for OS for median Trop-2 H-score subgroups by treatment arm among patients with (A) PD/SD and (B) CR/PR as best response to last prior anti-PD-(L)1–containing therapy.
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Trop-2 subgroup analysis of OS.
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Representativeness of study patients
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Trop-2 subgroup analysis of PFS.
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Genomic alteration landscape based on the HRR 24-gene list.
Accès ouvert
2026
other
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Oncogenic driver alterations. A, ctDNA oncogenic driver alteration landscape at baseline showing only cases harboring an alteration. Kaplan–Meier plots for OS by (B) KRAS mutation status and treatment arm, (C) EGFR, ALK, ROS1, and RET combined mutation status based on ctDNA only …
Accès ouvert
2026
supplementary-materials
OpenAlex
Enriqueta Felip, Peiwen Kuo, Pilar Garrido, C. Chouaïd et autres
Mutation landscape of the 20 most frequently mutated DDR genes in baseline ctDNA for patients with (A) nonsquamous and (B) squamous histology, adjusted for TP53.