Accès ouvert
2024
article
OpenAlex
Astrid Marchal, Elizabeth T. Cirulli, Iva Neveux, Evangelos Bellos et autres
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B∗15:01 allele and asymptomatic SARS-CoV-2 infection in unvaccinated individuals was recently reported, suggesting a contribution of …
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Accès ouvert
2024
erratum
OpenAlex
Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang et autres
International audience
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Accès ouvert
2023
article
OpenAlex
Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang et autres
Abstract Background We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15–20% of cases of life-threatening COVID-19 in unvaccinated patients. …
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