LARGE-SCALE IN VIVO POOLED SCREENING IN EQUINE JOINTS ACCELERATES HIT-TO-LEAD DISCOVERY FOR OSTEOARTHRITIS
Neety Sahu, Chris Towne, Vinay K. Kartha, Linda Chio et autres
0 citationsOsteoarthritis and Cartilage
Martin Borch Jensen
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76Publications signalées
2021Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model OrganismsCancer, Hypoxia, and MetabolismOsteoarthritis Treatment and MechanismsLiver Disease Diagnosis and Treatment
Publications récentes
A Multispecies, Modality-Agnostic Scalable In Vivo Mosaic Screening Platform for Therapeutic Target Discovery
Vishwaraj Sontake, Vinay K. Kartha, Neety Sahu, Daniel Fuentes et autres
0 citationsbioRxiv (Cold Spring Harbor Laboratory)
Ferret model of bleomycin-induced lung injury shares features of human idiopathic pulmonary fibrosis
Shuang Wu, Ian D. Driver, Meihui Luo, Hikaru Miyazaki et autres
6 citationsnpj Regenerative Medicine
Abstract 4359422: Low-Dose GLP-1 Receptor Agonist Therapy Exerts Anti-Fibrotic Effects Across Multiple Organs in Cardiometabolic HFpEF
Mahmoud H. Elbatreek, Natalie Gehred, Tatiana Gromova, Zhen Li et autres
0 citationsCirculation
Abstract 4366419: GLP-1 Receptor Agonist Semaglutide Improves Hepatic Metabolism and Reverses Hepatic Steatosis Independent of Weight Loss in Cardiometabolic HFpEF
Natalie Gehred, Tatiana Gromova, Mahmoud H. Elbatreek, Zhen Li et autres
0 citationsCirculation
Abstract 4368091: Identification of therapeutic targets in heart failure with preserved ejection fraction using a novel in vivo screen system
Naoto Muraoka, Gavin Pharaoh, Tolga Berkman, Shengping Wang et autres
0 citationsCirculation
Abstract 4368026: Comprehensive echocardiographic analysis of optimized rodent models of heart failure with preserved ejection fraction identifies superior LV filling pressure surrogates
Naoto Muraoka, Gavin Pharaoh, Tolga Berkman, Shengping Wang et autres
0 citationsCirculation
MON-698 High-Throughput In Vivo Pooled Mosaic Screening in Adipose, Heart, and Liver Identifies Novel Targets for Metabolic Diseases
Joanne Hsieh, Naoto Muraoka, Shengping Wang, Gavin Pharaoh et autres
0 citationsJournal of the Endocrine Society
SUN-697 Profiling Hepatokine Gene Expression in a Nonhuman Primate Model at Single Nucleus Resolution for Application to in Vivo Mosaic Screening in Other Species to Gain Insights Into Obesity Phenotypes
Joanne Hsieh, Vinay K. Kartha, Jingshu Chen, Shengping Wang et autres
0 citationsJournal of the Endocrine Society
Low Dose GLP-1 Therapy Attenuates Pathological Cardiac and Hepatic Remodelling in HFpEF Independent of Weight Loss
Mahmoud H. Elbatreek, Zhen Li, Xiaoman Yu, Natalie Gehred et autres
2 citationsbioRxiv (Cold Spring Harbor Laboratory)
Late Breaking Abstract - High-throughput in vivo functional genomics screen identifies therapeutic candidates that regulate lung physiology and ECM synthesis in pulmonary fibrosis
Vishwaraj Sontake, Chun‐Biu Li, Shengping Wang, Vinay K. Kartha et autres
0 citations
Dysregulated Protein s -Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure With Preserved Ejection Fraction
Zhen Li, Kyle B. LaPenna, Natalie Gehred, Xiaoman Yu et autres
11 citationsCirculation Research
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