Yago L. Nieto

Utility of Circulating Tumor DNA as a Monitoring Tool for Marker-Negative Germ Cell Tumors and Somatic Type Malignancies

Zachariah Thomas, Michael Glover, Andrew C. Johns, Emanuele Crupi et autres

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Phase I/II Trial of Evomela for Autologous Transplant in Myeloma: Schedule Optimization and Matched Comparison with MEL200

Qaiser Bashir, Peter F. Thall, Jitesh Kawedia, Xun Xu et autres

Melphalan 200 mg/m² is the standard conditioning regimen for autologous hematopoietic stem cell transplantation (ASCT) in multiple myeloma, but further dose escalation is limited by toxicity. Evomela, a propylene‑glycol-free melphalan with enhanced stability, enables safer dose intensification and pharmacokinetic (PK) optimization. We …

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The Pitfalls of Categorizing Donor Age: Arbitrary Cutoffs Fail to Predict Survival in Haploidentical HCT

Yosra M. Aljawai, Denai Milton, Rohtesh S. Mehta, Portia Smallbone et autres

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Prognostic impact of monosomy 13 and deletion of 13q in multiple myeloma patients undergoing upfront autologous transplantation

Damian Mikulski, Curtis Marcoux, Mark R. Tanner, Qaiser Bashir et autres

Deletion (13q)/monosomy 13 (del[13q]/-13) is common in multiple myeloma (MM), but its independent prognostic value remains unclear, particularly in patients treated with modern therapy and upfront autologous haematopoietic stem cell transplantation (autoHSCT). This study aimed to assess its impact on progression-free survival …

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Carfilzomib, lenalidomide, and dexamethasone (KRd) versus bortezomib, lenalidomide, and dexamethasone (VRd) induction prior to autologous haematopoietic stem cell transplant/transplantation in newly diagnosed multiple myeloma

Curtis Marcoux, Denái R. Milton, Mark R. Tanner, Qaiser Bashir et autres

Bortezomib, lenalidomide and dexamethasone (VRd) and carfilzomib, lenalidomide and dexamethasone (KRd) regimens have been widely used for induction in transplant-eligible newly diagnosed multiple myeloma (NDMM), yet direct comparisons between these regimens have been limited and inconsistent. We retrospectively analysed 1129 NDMM patients …

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A Simplified Frailty Score Predicts Outcomes in Newly Diagnosed Multiple Myeloma Patients Undergoing Upfront Autologous Hematopoietic Stem Cell Transplantation

Chelby Wakefield, Curtis Marcoux, Denái R. Milton, Mark R. Tanner et autres

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Divergent biology and outcomes of somatic transformations in germ cell tumors

Z Thomas, Andrew C. Johns, Michael Glover, Emanuele Crupi et autres

PURPOSE: Somatic-type malignancy (SM) of germ cell tumor (GCT) is rare but demonstrates aggressive behavior. Differences by primary site, time to transformation, and mutational status remain poorly characterized. PATIENTS AND METHODS: We reviewed all SM patients between June 2016 and May 2025 …

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Donor-specific HLA mismatch: haploidentical versus 7/8 mismatched unrelated donor hematopoietic cell transplantation with PTCy

Yosra M. Aljawai, Kai Cao, Jun Zou, Yudith Carmazzi et autres

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Randomized Trial of Two Fractionation Schedules of Myeloablative Busulfan with Fludarabine and Cladribine in Acute Myeloid Leukemia or Myelodysplastic Syndromes

Uday Popat, Konstantinos Lontos, Roland Bassett, Jitesh Kawedia et autres

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Large-Cell Transformation in Mycosis Fungoides and Sezary syndrome: A Single-Institution Experience at MD Anderson Cancer Center

Rishabh Lohray, Jordan Lily Jafarnia, Sage Copling, Sai Sarnala et autres

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Results of delayed or salvage autologous hematopoietic stem cell transplantation for multiple myeloma

Oren Pasvolsky, Curtis Marcoux, Denái R. Milton, Asad A. Haider et autres

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Ex vivo mesenchymal progenitor cell-based cord blood cell expansion and exofucosylation to enhance transplant engraftment

Portia Smallbone, Mayela Carolina Mendt, Robert Sackstein, Mark R. Tanner et autres

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