Rimantas Baušys

Circulating miR-21 and miR-181a as Biomarkers for Predicting Postoperative Complications Following Colorectal Cancer Resection: A Longitudinal Observational Study

Kornelija Rauduvytė, Marius Kryžauskas, Domas Drazdauskas, Vilius Ogaras et autres

Background/Objectives: Early and accurate detection of postoperative complications (POCs) remains a major challenge in colorectal cancer (CRC) surgery, underscoring the need for reliable molecular biomarkers. This study evaluated whether plasma miR-21 and miR-181a can predict POCs following left-sided CRC resection. Methods: This …

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Preoperative TNF-α as a Novel Biomarker for Predicting Postoperative Outcomes in Colorectal Cancer Surgery

K. Rauduvytė, Paulina Kazlauskaitė, Marius Kryžauskas, Povilas Ignatavičius et autres

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Circulating miR-19, miR-27a, and miR-200c as novel biomarkers for resistance to neoadjuvant chemotherapy in gastric cancer patients: a pilot study

Bernardas Baušys, Kornelija Rauduvytė, Agnė Šeštokaitė, Klaudija Bičkaitė et autres

Background Neoadjuvant chemotherapy (NAC) is a standard approach for treating locally advanced gastric cancer (GC), but resistance in some patients can result in treatment toxicity and surgical delays without therapeutic benefit. Identifying biomarkers predictive of NAC response is crucial for personalized treatment …

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Preoperative TNF-α predicts uneventful postoperative outcomes in patients undergoing colorectal cancer surgery

Kornelija Rauduvytė, Paulina Kazlauskaitė, Marius Kryžauskas, Povilas Ignatavičius et autres

The development of novel biomarkers to predict postoperative complications (POCs) after colorectal cancer (CRC) surgery is essential, both for improving treatment outcomes and for facilitating the widespread use of same-day discharge following colectomy. This longitudinal observational study, a sub-study of a previous …

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Gut Microbiome Changes After Neoadjuvant Chemotherapy and Surgery in Patients with Gastric Cancer

Kristina Žukauskaitė, Bernardas Baušys, Angela Horvath, Rasa Sabaliauskaitė et autres

Background/Objectives: Neoadjuvant chemotherapy (NAC) followed by radical gastrectomy is the current standard approach for locally advanced gastric cancer (GC) in the West. Both NAC and gastrectomy can significantly influence the gut microbiome, potentially leading to clinically significant changes. However, no longitudinal studies …

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Circulating microRNAs as a marker predicting chemoresistance to neoadjuvant chemotherapy in gastric cancer

Bernardas Baušys, Kristina Žukauskaitė, Rasa Sabaliauskaitė, Kornelija Rauduvytė et autres

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Interim results of PIPAC with cisplatin and doxorubicin in combination with FOLFOX chemotherapy as a first-line treatment for gastric cancer with peritoneal metastases: single-arm phase II study

Martynas Lukšta, Augustinas Baušys, Klaudija Bičkaitė, R. Rackauskas et autres

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Gut Microbiome Changes Through Radical Treatment of Advanced Gastric Cancer: Neoadjuvant Chemotherapy and Gastrectomy Effects

K. Žukauskaitė, Bernardas Baušys, R. Sabaliauskaitė, A Horváth et autres

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Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for Gastric Cancer Peritoneal Metastases: Results from the Lithuanian PIPAC Program

Martynas Lukšta, Augustinas Baušys, Neda Gendvilaitė, Klaudija Bičkaitė et autres

Background: Peritoneal metastases (PM) of gastric cancer (GC) are considered a terminal condition, with reported median survival ranging from 2 to 9 months. Standard treatment typically involves systemic chemotherapy alone or combined with targeted therapy or immunotherapy, though efficacy is limited. Pressurized …

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Impact of mechanical bowel preparation on the gut microbiome of patients undergoing left-sided colorectal cancer surgery: randomized clinical trial

Kristina Žukauskaitė, Angela Horvath, Žilvinas Gricius, Mindaugas Kvietkauskas et autres

BACKGROUND: Postoperative complications after colorectal cancer surgery have been linked to the gut microbiome. However, the impact of mechanical bowel preparation using oral preparation agents or rectal enema on postoperative infections remains poorly understood. This study aimed to compare the impact of …

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Short- and long-term outcome differences between patients undergoing left and right colon cancer surgery: cohort study

Justas Kuliavas, Kristina Marcinkevičiūtė, Augustinas Baušys, Klaudija Bičkaitė et autres

PURPOSE: Since the literature currently provides controversial data on the postoperative outcomes following right and left hemicolectomies, we carried out this study to examine the short- and long-term treatment outcomes. METHODS: This study included consecutive patients who underwent right or left-sided colonic …

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Achieving Textbook Outcomes in Colorectal Cancer Surgery Is Associated with Improved Long-Term Survival: Results of the Multicenter Prospective Cohort Study

Marius Kryžauskas, Augustinas Baušys, Vilius Abeciūnas, Austėja Elžbieta Degutytė et autres

Background: The outcomes of patients with colorectal cancer greatly depend on the quality of their surgical care. However, relying solely on a single quality indicator does not adequately capture the multifaceted nature of modern perioperative care. A new tool—“Textbook Outcome” (TO)—has been …

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