Intratumoral heterogeneity and clonal evolution in liver cancer
B Losic, Craig Aj, C Villacorta-Martin, SN Martins-Filho et autres
Clonal evolution of a tumor ecosystem depends on different selection pressures that are principally immune and treatment mediated. We integrate RNA-seq, DNA sequencing, TCR-seq and SNP array data across multiple regions of liver cancer specimens to map spatio-temporal interactions between cancer and …
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