Carolina Abrutzky

Nasal Epinephrine Spray For Anaphylaxis: Which Is Better - Powder Or Liquid?

Tair Lapidot, Yuval Tal, Galia Temtsin Krayz, Anna Berman et autres

FMXIN002 Epinephrine Intranasal Powder Spray Is Stable Throughout 3 Freeze-Thaw Cycles

Tair Lapidot, Yuval Tal, Galia Temtsin Krayz, Anna Berman et autres

First-in-class intranasal epinephrine spray for anaphylaxis: Dose finding clinical study

Tair Lapidot, Yuval Tal, Dalia Megiddo, Galia Temtsin Krayz et autres

Background Anaphylaxis is a life-threatening clinical presentation of acute systemic allergic reactions. Timely administration of epinephrine, usually by intramuscular autoinjector, is a robust life-saving treatment. Despite the critical necessity, there are multiple deterrents to patients' proper use of epinephrine autoinjectors. FMXIN002 is …

il (code pays fourni par la source)

Fast Acting, Dry Powder, Needle-Free, Intranasal Epinephrine Spray: A Promising Future Treatment for Anaphylaxis

Yuval Tal, Yaarit Ribak, Limor Rubin, Aviv Talmon et autres

BACKGROUND: Epinephrine intramuscular (IM) autoinjector is a life-saving drug for the emergency treatment of immediate-type allergic reactions (type I). Nevertheless, it is sometimes applied incorrectly or underused because of short shelf life, high costs, fear of use, or inconvenience of carrying. FMXIN002, …

il, ca, us (code pays fourni par la source)

A Novel Faster-Acting, Dry Powder-Based, Naloxone Intranasal Formulation for Opioid Overdose

Tair Lapidot, Mohammed Bouhajib, Janice Faulknor, Shabaz Khan et autres

OBJECTIVE: To examine the pharmacokinetics and safety of FMXIN001, a new intranasal powder-based naloxone formulation, in comparison to Narcan® nasal liquid spray. METHODS: FMXIN001, was developed by blending drug microspheres with larger lactose monohydrate particles, that serve as diluent and carrier, as …

us, ca, il (code pays fourni par la source)