Veena Sangwan

Figure S3 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

Verification of the inducible UXS1 expression and knockdown by RT-qPCR.

Figure S5 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

Verification of the reference and variant sequences of the luciferase constructs.

Table S6 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

SNV filtering using HiChIP data referenced in manuscript

Figure S2 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

UXS1 is a selective dependency in gastroesophageal cancers.

Table S1 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

GEC risk-associated index SNVs and loci.

Figure S4 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

The rs147518036 SNV genotypes for the gastric cancer cell lines.

Table S3 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

List of files used from ENCODE

Table S2 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

ldSNVs for each GWAS index SNV (r2 ≥ 0.8)

Table S4 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

Primer List

Table S5 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

List of genes and their LRT scores surrounding each GWAS index SNV.

Figure S1 from HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer

Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White et autres

Expression of UXS1 in normal and tumor tissues.

Optimized Large-Scale Longitudinal Biorepository of Gastroesophageal Adenocarcinoma Patient-Derived Organoids: High-Fidelity Models for Personalized Treatment to Overcome Resistance

Mingyang Kong, Sanjima Pal, Shuyuan Wang, Julie Bérubé et autres

A major limitation in studying gastroesophageal adenocarcinoma (GEA) has been the lack of reliable models that represent the disease’s complexity. We present lessons learned from a comprehensive large-scale biobanking effort combining traditional sample collection with several in vitro models, including 3-dimensional patient-derived …

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