Accès ouvert
2023
article
OpenAlex
Treefa Shwani, Charles Zhang, Leah A. Owen, Akbar Shakoor et autres
Age-related macular degeneration (AMD) is a leading cause of blindness, and elucidating its underlying disease mechanisms is vital to the development of appropriate therapeutics. We identified differentially expressed genes (DEGs) and differentially spliced genes (DSGs) across the clinical stages of AMD in …
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Luz D. Orozco, Leah A. Owen, Jeffrey W. Hofmann, Amy Stockwell et autres
Age-related macular degeneration (AMD) is a leading cause of blindness, affecting 200 million people worldwide. To identify genes that could be targeted for treatment, we created a molecular atlas at different stages of AMD. Our resource is comprised of RNA sequencing (RNA-seq) …
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Luz D. Orozco, Leah A. Owen, Jeffrey W. Hofmann, Amy Stockwell et autres
Age-related Macular Degeneration (AMD) is a leading cause of blindness, affecting 200 million people worldwide. We present a comprehensive molecular atlas for different stages of AMD.
Accès ouvert
2022
preprint
OpenAlex
Charles Zhang, Julie L. Barr, Leah A. Owen, Akbar Shakoor et autres
Abstract Age-related macular degeneration (AMD) is a complex neurodegenerative disease and is the leading cause of blindness in the aging population. Early AMD is characterized by drusen in the macula and causes minimal changes in visual function. The later stages are responsible …
us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Luz D. Orozco, Leah A. Owen, Jeffrey W. Hofmann, Amy Stockwell et autres
Age-related Macular Degeneration (AMD) is a leading cause of blindness, affecting 200 million people worldwide. We present a comprehensive molecular atlas for different stages of AMD.