Accès ouvert
2023
article
OpenAlex
Severin A. Lautenschlager, Mamadou Pathé Barry, Gerhard Rogler, Luc Biedermann et autres
BACKGROUND: Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis. METHODS: 2294 patients from the Swiss IBD Cohort …
ch
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Priyatharsan Yoganathan, Jean‐Benoît Rossel, Sebastian Bruno Ulrich Jordi, Yannick Franc et autres
BACKGROUND: Genetic variations within the regulatory region of the gene encoding NOD-like receptor pyrin domain containing 3 (NLRP3) have been associated with Crohn's Disease (CD). NLRP3 is part of the NLRP3-inflammasome that mediates the maturation of IL-1β and IL-18. Carrying the major …
ch
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Alexander Reinhard Siebenhüner, Jean‐Benoît Rossel, Philipp Schreiner, Matthias Butter et autres
BACKGROUND AND AIMS: Anxiety and depression are prevalent in patients with inflammatory bowel diseases (IBD), especially during IBD flares. IBD therapies can profoundly affect the mood of patients with IBD. We aimed to determine the long-term impact of anti-tumor necrosis factor (anti-TNF) …
ch
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Philipp Wuggenig, Berna Kaya, Hassan Bachir Melhem, C. Korcan Ayata et autres
Abstract Comprehensive development is critical for gut macrophages being essential for the intestinal immune system. However, the underlying mechanisms of macrophage development in the colon remain elusive. To investigate the function of branched-chain amino acids in the development of gut macrophages, an …
ch
(code pays fourni par la source)