Aurélia Leroux

New Diagnostic Score for Sepsis in Adult Horses with Acute Gastrointestinal Disease

Angélique Blangy-Letheule, Jérôme Montnach, Julien Perrier, Louise Lemonnier et autres

Colic is a leading cause of mortality in horses, particularly when associated with systemic inflammation and organ dysfunction. In human medicine, these complications are associated with sepsis, defined as organ dysfunction caused by a dysregulated, life-threatening host response to infection. However, no …

fr (code pays fourni par la source)

Platelet Preservation and Functionality in Blood Treated for Autotransfusion: A Comparative In Vitro Study on Human Blood and In Vivo Study Using a Massive Hemorrhage Swine Model

Marine Schott, Estelle Leroux, Chloé Libaud, Audrey Lafragette et autres

During hemorrhagic procedures, autotransfusion is one of the main strategies for patient blood management. While conventional cell savers only concentrate red blood cells due to the centrifugation method, the innovative same™ autotransfusion medical device (i-SEP, Nantes, France), based on a hollow-fiber filtration …

fr (code pays fourni par la source)

New Diagnostic Score for Sepsis in Adult Horses with Acute Gastrointestinal Disease

Angélique Blangy‐Letheule, Jérôme Montnach, M. Denis, Bertrand Rozec et autres

Context: Colic is a major equine disease with significant medical and economic impacts. It remains a leading cause of mortality, due to its frequent progression to systemic inflammation and organ dysfunction. As in human medicine, these complications are associated with sepsis, defined …

fr (code pays fourni par la source)

Equine piroplasmosis in different geographical areas in France: Prevalence heterogeneity of asymptomatic carriers and low genetic diversity of Theileria equi and Babesia caballi

Maggy Jouglin, Claire Bonsergent, de la Cotte N, M Mège et autres

Equine piroplasmosis is a worldwide tick-borne disease caused by the parasites Theileria equi sensu lato and Babesia caballi, with significant economic and sanitary consequences. These two parasites are genetically variable, with a potential impact on diagnostic accuracy. Our study aimed to evaluate …

fr, Maroc (code pays fourni par la source)

Equine piroplasmosis in different geographical areas in France: prevalence heterogeneity of asymptomatic carriers and low genetic diversity of Theileria equi and Babesia caballi

Maggy Jouglin, Claire Bonsergent, Nathalie de la Cotte, M Mège et autres

Abstract Equine piroplasmosis is a worldwide tick-borne disease caused by the protozoan parasites Theileria equi and Babesia caballi , with significant economic and sanitary consequences. It can also limit the export of infected horses to piroplasmosis-free countries. These two parasites are genetically …

fr (code pays fourni par la source)

Value of a secretomic approach for distinguishing patients with COVID‐19 viral pneumonia among patients with respiratory distress admitted to intensive care unit

Angélique Blangy‐Letheule, Amandine Vergnaud, Thomas Dupas, Damien Habert et autres

In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with Nonviral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand the molecular pathophysiology of viral pneumonia and to search for …

fr (code pays fourni par la source)

O-GlcNAcylation levels remain stable regardless of the anesthesia procedure in healthy rats

Martin Bouaud, Amandine Vergnaud, Thomas Pelé, Angélique Blangy‐Letheule et autres

fr (code pays fourni par la source)

O-GlcNAcylation levels remain stable regardless of the anaesthesia in healthy rats

Thomas Dupas, Amandine Vergnaud, Thomas Pelé, Angélique Blangy‐Letheule et autres

Anaesthetics are used daily in human and veterinary medicine as well as in scientific research. Anaesthetics have an impact on cell homeostasis especially through modulation of protein post-translational modifications. O-GlcNAcylation, a ubiquitous post-translational modification, plays a role in many biological processes. The …

fr, ca (code pays fourni par la source)

9. Piroplasmose équine : portage asymptomatique et diversité génétique des deux parasites responsables

M. Jouglin, Florian Berquier, Philippe Benezech, Claire Bonsergent et autres

fr (code pays fourni par la source)

Developing a Clinically Relevant Hemorrhagic Shock Model in Rats

Thomas Dupas, Virginie Aillerie, Amandine Vergnaud, Thomas Pelé et autres

Over the recent decades, the development of animal models allowed us to better understand various pathologies and identify new treatments. Hemorrhagic shock, i.e., organ failure due to rapid loss of a large volume of blood, is associated with a highly complex pathophysiology …

fr (code pays fourni par la source)

Equine Piroplasmosis in Different Geographical Areas in France: Prevalence Heterogeneity of Asymptomatic Carriers and Low Genetic Diversity of Theileria Equi and Babesia Caballi

Maggy Jouglin, Bonsergent Claire, Nathalie de la Cotte, Mickäel Mège et autres

fr (code pays fourni par la source)

Complete title: Value of a secretomic approach for distinguishing patients with COVID-19 viral pneumonia among patients with respiratory distress admitted to intensive care unit Shortened title: Secretomic to distinguish COVID-19 patients

Angélique Blangy‐Letheule, Amandine Vergnaud, Thomas Dupas, Damien Habert et autres

Introduction : In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with non-viral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand the molecular pathophysiology of viral pneumonia and to …

fr (code pays fourni par la source)