Caihua Sang

Thromboembolism and Bleeding Risks in Atrial Fibrillation: Outcomes of Oral Anticoagulation After Catheter Ablation

Lan Ren, Xiaodong Peng, Sitong Li, Jue Wang et autres

Background Despite the growing use of catheter ablation for atrial fibrillation, large‐scale studies assessing the efficacy and safety of oral anticoagulation (OAC) after ablation, particularly in patients with high stroke risk, remain limited. Methods This prospective study enrolled consecutive patients from the …

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Residual thromboembolic risk and outcomes of oral anticoagulation discontinuation after atrial fibrillation ablation: a target trial emulation

Xiaodong Peng, Liu He, Jue Wang, Sitong Li et autres

AIMS: Optimal management of oral anticoagulation (OAC) after atrial fibrillation (AF) ablation remains uncertain. We evaluated thromboembolic and bleeding outcomes associated with OAC discontinuation vs. continuation at a clinically relevant 6-month post-ablation landmark. METHODS AND RESULTS: This target trial emulation used data …

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Delayed Pericardial Effusion Following Ethanol Infusion of the Vein of Marshall

Fengyuan Lu, Yongmei Zhang, Xiaodong Peng, Fanchao Meng et autres

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Comparison of Ablation Index‐Guided Lesion Size in nGEN and SMARTABLATE: An Ex Vivo Porcine Heart Study

Xinru Li, Jie-wen Yin, Xue‐Si Wang, Yang‐Yang Feng et autres

ABSTRACT Background nGEN TM generator is a new‐generation radiofrequency (RF) energy device widely used in the catheter ablation of atrial fibrillation. Compared with SMARTABLATE TM (SMA), a lower displayed impedance of nGEN can be observed during electrophysiology procedures. However, whether this impedance …

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Validation of Smartwatches Integrated With Photoplethysmography for Continuous Evaluation of Atrial Fibrillation Burden

Song Zuo, Le Zhou, Han Feng, Christian Massad et autres

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Ablation versus drug therapy in atrial fibrillation patients with or without prior Pharmacological or direct current cardioversion: results from the CABANA trial

Wenli Dai, Zejun Yang, Sitong Li, Mingxiao Li et autres

BACKGROUND: Catheter ablation is superior to drug therapy in selected atrial fibrillation (AF) patients, yet the impact of prior non-ablation rhythm control remains unclear. METHODS: We analyzed data from Catheter Ablation vs. Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) trial, which assessed …

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Mental health status and cardiovascular outcomes across Life's Essential 8 categories

Enze Li, Le Zhou, Liu He, Song Zuo et autres

Anxiety and depression are established risk factors for cardiovascular disease (CVD); impacts of these conditions on cardiovascular outcomes across different levels of cardiovascular health (CVH), measured by Life's Essential 8 (LE8) scores, remain unclear. We analyzed 290,778 UK Biobank participants (mean age …

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Dapagliflozin to Reduce Early Recurrence After Catheter Ablation for Atrial Fibrillation: The DARE-AF Randomized Clinical Trial

Chao Jiang, Zixu Zhao, Zejun Yang, Xu Yang et autres

BACKGROUND: Observational studies have suggested that SGLT2 (sodium-glucose cotransporter 2) inhibitors are associated with a lower risk of atrial fibrillation (AF) recurrence after catheter ablation in patients with AF with concomitant diabetes, heart failure, or chronic kidney disease. However, no randomized trial …

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Catheter ablation is associated with reduced cardiovascular events in atrial fibrillation patients with atrial functional mitral regurgitation

Qifan Li, Xiaodong Peng, Yiwei Lai, He Liu et autres

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Effectiveness of Catheter Ablation for Patients With Atrial Fibrillation and Heart Failure

Le Zhou, Jue Wang, Liu He, Xiangyi Kong et autres

BACKGROUND: Atrial fibrillation (AF) is frequently complicated by heart failure (HF), leading to increased morbidity and mortality. Catheter ablation (CA) has been shown in randomized controlled trials (RCTs) to improve outcomes in selected patients with AF and heart failure with reduced ejection …

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Catheter Ablation for Ventricular Tachycardia in Patients With Hypertrophic Cardiomyopathy

Shuyu Jin, Mengmeng Li, Chenxi Jiang, Ribo Tang et autres

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Orthostatic Systolic Blood Pressure Elevation and Incident Atrial Fibrillation: Insights From the SPRINT Trial

Jue Wang, Wenhe Lv, Zhen Wang, Sitong Li et autres

Exaggerated orthostatic changes in systolic blood pressure (SBP) were associated with adverse cardiovascular events. We aim to assess the association between orthostatic SBP changes and incident atrial fibrillation (AF). We performed a post hoc analysis of SPRINT (Systolic Blood Pressure Intervention Trial). …

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