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Giovanni Maria Ferrari, Vitaly Terushkin, Martin J. Wolff, Xiaodong Zhang et autres
PDF file - 51K
Giovanni Maria Ferrari, Vitaly Terushkin, Martin J. Wolff, Xiaodong Zhang et autres
PDF file - 51K
Giovanni Maria Ferrari, Vitaly Terushkin, Martin J. Wolff, Xiaodong Zhang et autres
Abstract TGF-β1 and VEGF, both angiogenesis inducers, have opposing effects on vascular endothelial cells. TGF-β1 induces apoptosis; VEGF induces survival. We have previously shown that TGF-β1 induces endothelial cell expression of VEGF, which mediates TGF-β1 induction of apoptosis through activation of p38 …
Giovanni Maria Ferrari, Vitaly Terushkin, Martin J. Wolff, Xiaodong Zhang et autres
Abstract TGF-β1 and VEGF, both angiogenesis inducers, have opposing effects on vascular endothelial cells. TGF-β1 induces apoptosis; VEGF induces survival. We have previously shown that TGF-β1 induces endothelial cell expression of VEGF, which mediates TGF-β1 induction of apoptosis through activation of p38 …
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
Abstract The urokinase-type plasminogen activator receptor (uPAR) has a well-established role in cancer progression, but it has been little studied at earlier stages of cancer initiation. Here, we show that uPAR deficiency in the mouse dramatically reduces susceptibility to the classical two-stage …
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
Abstract The urokinase-type plasminogen activator receptor (uPAR) has a well-established role in cancer progression, but it has been little studied at earlier stages of cancer initiation. Here, we show that uPAR deficiency in the mouse dramatically reduces susceptibility to the classical two-stage …
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
This file include Supplementary Figure Legends
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
This file include more detailed Material and Methods
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
This file include Supplementary Figures S1-7 and Tables S1-2. Figure S1. Inflammation and neo-angiogenesis are not impaired in TPA-treated uPAR-/- skin. Figure S2. Distinct stages of hair cycling in uPAR+/+ and uPAR-/- littermates. Figure S3. FACS isolation of K14-GFP-actin/uPAR+/+ and K14-GFP-actin/uPAR-/- mouse …
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
This file include Supplementary Figure Legends
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
This file include Supplementary Figures S1-7 and Tables S1-2. Figure S1. Inflammation and neo-angiogenesis are not impaired in TPA-treated uPAR-/- skin. Figure S2. Distinct stages of hair cycling in uPAR+/+ and uPAR-/- littermates. Figure S3. FACS isolation of K14-GFP-actin/uPAR+/+ and K14-GFP-actin/uPAR-/- mouse …
Roberta Mazzieri, Giovanni Pietrogrande, Laura Gerasi, Alessandro Gandelli et autres
This file include more detailed Material and Methods
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