Accès ouvert
2024
conference-abstract
OpenAlex
Eva Castellano, Almudena García-Ortiz, Laura Ugalde, Elena Maroto Martín et autres
Despite significant advances in the treatment strategies for Multiple Myeloma (MM), there is still a significant proportion of patients who will progress due to therapy resistances. CAR NK immunotherapy has recently emerged as a cost-effective and safer therapeutic alternative in relapsed/refractory cancer …
es
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Eva Castellano, Almudena García-Ortiz, Laura Ugalde, Elena Maroto-Martín et autres
2023
conference-abstract
OpenAlex
Jessica Encinas, Almudena García-Ortiz, Elena Maroto-Martín, Eva Castellano et autres
us, it, es
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Jessica Encinas, Almudena García-Ortiz, Elena Maroto-Martín, Eva Castellano et autres
Background: HLA-E is highly expressed in several tumor cells, including metastatic cells, and correlates with a poor prognosis. Its interaction with the inhibitory receptor NKG2A, expressed in T lymphocytes and NK cells, enables tumor cell escape. Although α-NKG2A antibodies have not shown …
es, us
(code pays fourni par la source)
2022
conference-abstract
OpenAlex
Elena Maroto Martín, Jessica Encinas, Almudena García-Ortiz, Eva Castellano et autres
2021
conference-abstract
OpenAlex
Elena Maroto Martín, Jessica Encinas, Almudena García-Ortiz, Eva Castellano et autres
es, us
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Unai Perpiñá, Cristina Herranz, Raquel Martín‐Ibáñez, Anna Boronat et autres
Abstract Background Cell banks are widely used to preserve cell properties as well as to record and control the use of cell lines in biomedical research. The generation of cell banks for the manufacturing of Advanced Therapy Medicinal Products, such as cell …
es, us
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Unai Perpiñá, Cristina Herranz, Raquel Martín‐Ibáñez, Anna Boronat et autres
Abstract Background: Cell banks are widely used to preserve cell properties as well as to record and control the use of cell lines in biomedical research. The generation of cell banks for the manufacturing of Advanced Therapy Medicinal Products, such as cell …
es
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Valentín Ortiz‐Maldonado, Susana Rives, María Castellà, Anna Alonso‐Saladrigues et autres
We evaluated the administration of ARI-0001 cells (chimeric antigen receptor T cells targeting CD19) in adult and pediatric patients with relapsed/refractory CD19 + malignancies. Patients received cyclophosphamide and fludarabine followed by ARI-0001 cells at a dose of 0.4–5 × 10 6 ARI-0001 …
es
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Unai Perpiñá, Cristina Herranz, Raquel Martín‐Ibáñez, Anna Boronat et autres
Abstract Background: Cell banks have been widely used to preserve cell properties as well as to record and control cell line access in research. However, the generation of cell banks involved in the manufacturing of Advanced therapy medicinal products such as cell …
es
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Unai Perpiñá, Cristina Herranz, Raquel Martín‐Ibáñez, Anna Boronat et autres
es
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
María Castellà, Miguel Caballero‐Baños, Valentín Ortiz‐Maldonado, Europa Azucena González‐Navarro et autres
Development of semi-automated devices that can reduce the hands-on time and standardize the production of clinical-grade CAR T-cells, such as CliniMACS Prodigy from Miltenyi, is key to facilitate the development of CAR T-cell therapies, especially in academic institutions. However, the feasibility of …
es
(code pays fourni par la source)