Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations
Pritesh Jain, Hong Kiat Ng, Darwin Tay, Theresia Mina et autres
ABSTRACT To identify biomarkers and pathways to Type-2 diabetes (T2D), a major global disease, we completed array-based epigenome-wide association in whole blood in 5,709 Asian people. We found 323 Sentinel CpGs (from 314 genetic loci) that predict future T2D. The CpGs reveal …
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