Jean Cyr

Noninferiority of One HPV Vaccine Dose to Two Doses

Aimée R. Kreimer, Carolina Porras, Danping Liu, Allan Hildesheim et autres

BACKGROUND: Multidose human papillomavirus (HPV) vaccination is efficacious, yet the vaccine has been underused globally. Emerging data suggest that a single dose may provide protection. Whether a single dose of HPV vaccine would provide similar protection to two doses is uncertain. METHODS: …

us, cr, fr (code pays fourni par la source)

Rationale and design of a double-blind randomized non-inferiority clinical trial to evaluate one or two doses of vaccine against human papillomavirus including an epidemiologic survey to estimate vaccine efficacy: The Costa Rica ESCUDDO trial

Carolina Porras, Joshua N. Sampson, Rolando Herrero, Mitchell H. Gail et autres

HPV vaccination of adolescent girls is the most effective measure to prevent cervical cancer. The World Health Organization recommends that adolescent girls receive two doses of vaccine but only a small proportion of girls from regions with the highest disease burden are …

cr, us (code pays fourni par la source)

Rationale and design of a community-based double-blind randomized clinical trial of an HPV 16 and 18 vaccine in Guanacaste, Costa Rica

Rolando Herrero, Allan Hildesheim, Ana Cecilia Rodríguez, Sholom Wacholder et autres

cr, us (code pays fourni par la source)