D Couper

Age-dependent associations between 25-hydroxy Vitamin D levels and COPD symptoms: Analysis of SPIROMICS

I.Z Barjaktarevic, R.M. Burkes, W.W Labaki, Robert Paine et autres

Introduction: Age and vitamin D levels may affect symptom burden in chronic obstructive pulmonary disease (COPD). We used the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) to determine independent associations between vitamin D levels and COPD symptoms in different age …

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Nebulizer use in tobacco-exposed SPIROMICS participants with or at risk of COPD

J Fazio, A Hong, D Markovic, R. Graham Barr et autres

Rationale: Nebulizers are an alternative to handheld devices for providing inhaled therapy. We identified factors and trends associated with nebulizer use in SPIROMICS. Methods: SPIROMICS is a prospective cohort study with 2,981 enrolled participants across four strata, both never-smokers and smokers with …

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Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort.

Cooper CB, R Paine, Curtis JL, Kanner RE et autres

Christopher B Cooper,1 Robert Paine,2 Jeffrey L Curtis,3,4 Richard E Kanner,2 Carlos H Martinez,3 Catherine A Meldrum,3 Russell Bowler,5 Wanda O’Neal,6 Eric A Hoffman,7 David Couper,6 Miguel Quibrera,6 Gerald Criner,8 Mark T Dransfield,9 MeiLan K Han,3 Nadia N Hansel,10 Jerry A Krishnan,11 …