Elaine Spruce

Cost-Utility Analysis of Accelerated and Standard Strategies for Renal Replacement Therapy Initiation

Jeff Round, İlke Akpinar, Charles Yan, Natasha Patel et autres

Importance: Little is known about the long-term costs and outcomes related to strategies for timing of initiation of kidney replacement therapy (KRT) in critically ill patients with severe acute kidney injury (AKI). Objective: To estimate the cost-utility and cost-effectiveness of accelerated KRT …

ca, il, us (code pays fourni par la source)

The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study

Kirsty McGee, Md. Anower Hossain, Gavin D. Perkins, Anthony Gordon et autres

PURPOSE: The landiolol and organ failure in patients with septic shock (STRESS-L study) included a pre-planned sub-study to assess the effect of landiolol treatment on inflammatory and metabolomic markers. METHODS: Samples collected from 91 patients randomised to STRESS-L were profiled for immune …

gb (code pays fourni par la source)

Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis

Joel M. Dulhunty, Stephen J. Brett, Jan J. De Waele, Dorrilyn Rajbhandari et autres

Importance: Whether β-lactam antibiotics administered by continuous compared with intermittent infusion reduces the risk of death in patients with sepsis is uncertain. Objective: To evaluate whether continuous vs intermittent infusion of a β-lactam antibiotic (piperacillin-tazobactam or meropenem) results in decreased all-cause mortality …

au, gb, be, nz, sg, fr (code pays fourni par la source)

Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial

Ron Wald, Stèphane Gaudry, Bruno R. da Costa, Rinaldo Bellomo et autres

ca, fr, gb, au, cn, be, at, us, nz, ie, fi, ch (code pays fourni par la source)

Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial

Ary Serpa Neto, Orla M. Smith, M. Lynn Weir, Haibo Qiu et autres

ca, au, br, cn (code pays fourni par la source)

Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial

Sean M. Bagshaw, Ary Serpa Neto, Orla Smith, Matthew A. Weir et autres

ca, au, br, cn (code pays fourni par la source)

A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial

Fernando G. Zampieri, Bruno R. da Costa, François Lamontagne, Bram Rochwerg et autres

BACKGROUND: Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial compared two strategies of KRT initiation (accelerated versus standard) in critically ill patients with …

ca, br, fi, ie, au, nz, gb (code pays fourni par la source)