Yordi P.A. van Dooren

YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer

Bram Akerboom, Emily S.L. Martens, Milou A.M. Stals, Rolf E. Brouwer et autres

Importance: Although the YEARS algorithm is a safe and efficient way to rule out acute pulmonary embolism (PE), robust evidence on its accuracy in patients with cancer is lacking, and current guidelines suggest proceeding directly to computed tomographic pulmonary angiography (CTPA). Objective: …

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A study protocol for a randomised controlled trial evaluating the safety and efficiency of the YEARS algorithm versus computed tomography pulmonary angiography only for suspected acute pulmonary embolism in patients with cancer: the Hydra Study

Emily S.L. Martens, Bram Akerboom, Christine Baumgartner, Brouwer Re et autres

Abstract Background Pulmonary embolism (PE) is frequently suspected in patients with cancer due to non-specific symptoms suggestive of PE and their inherent risk of venous thromboembolism (VTE). Commonly used clinical decision rules (CDRs) and D-dimer testing may be less reliable in this …

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Noninvasive diagnostic work-up for suspected acute pulmonary embolism during pregnancy: a systematic review and meta-analysis of individual patient data

Milou A.M. Stals, Thomas Moumneh, Fionnuala Ní Áinle, Drahomir Aujesky et autres

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Ruling out Pulmonary Embolism in Patients with (Suspected) COVID-19—A Prospective Cohort Study

Milou A.M. Stals, Fleur H.J. Kaptein, Remy H.H. Bemelmans, Thomas van Bemmel et autres

Abstract Background Diagnostic strategies for suspected pulmonary embolism (PE) have not been prospectively evaluated in COVID-19 patients. Methods Prospective, multicenter, outcome study in 707 patients with both (suspected) COVID-19 and suspected PE in 14 hospitals. Patients on chronic anticoagulant therapy were excluded. …

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Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

L.M. van der Pol, Cécile Tromeur, Ingrid M. Bistervels, F. Ni Ainle et autres

(N Engl J Med. 2019;380(12):1139–1149. Doi:10.1056/NEJMoa1813865) Pregnancy and venous thromboembolism (VTE) share many symptoms and physiological changes, presenting a challenge for VTE diagnosis in pregnant women. The threshold for testing pregnant women for pulmonary embolism is low, as this population is at …

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Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

L.M. van der Pol, Cécile Tromeur, Ingrid M. Bistervels, Fionnuala Ní Áinle et autres

(Abstracted from N Engl J Med 2019;380:1139–1149) Acute pulmonary embolism is one of the leading causes of maternal death, with the overall incidence reported to be 1.72 cases per 1000 deliveries, accounting for approximately 1 death in every 100,000 deliveries. Since the …

Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

L.M. van der Pol, Cécile Tromeur, Ingrid M. Bistervels, Fionnuala Ní Áinle et autres

BACKGROUND: Pulmonary embolism is one of the leading causes of maternal death in the Western world. Because of the low specificity and sensitivity of the d-dimer test, all pregnant women with suspected pulmonary embolism undergo computed tomographic (CT) pulmonary angiography or ventilation-perfusion …

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O009: Safety and efficiency of the YEARS diagnostic algorithm for pregnant patients with clinically suspected acute pulmonary embolism: the ARTEMIS study

L.M. van der Pol, Cécile Tromeur, Ingrid M. Bistervels, Fionnuala NíAinle et autres