Susan Beth Kesmodel

The Doctor’s Doctor Is the Patient’s Doctor: A Pilot Quality Improvement Study on Patient-Pathologist Consultations at a Single Institution

Katherine Drews-Elger, Merce Jorda, Melissa Stedman, Sophie C. Egea et autres

Context.—: Pathologists have traditionally worked behind the scenes, providing diagnostic information to clinicians. The 21st Century Cures Act grants patients immediate access to pathology reports, creating opportunities and challenges for patient-pathologist communication. Objective.—: To evaluate the feasibility, acceptance, educational value, and perceived …

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Can Excision be Avoided for Atypical Ductal Hyperplasia of the Breast Diagnosed on Core Biopsy?

Youley Tjendra, Jamie Rosenkrantz Spoont, Laurence M. Briski, Nicolas C. Millan et autres

Background: Atypical ductal hyperplasia (ADH) diagnosed on core biopsy (CB) is associated with an upgrade risk to ductal carcinoma in situ (DCIS) or invasive carcinoma on surgical excision (SE). Although single institutional studies have shown observation and surveillance can be considered in …

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Breast Surgical Perspectives on the NSABP B-51/RTOG 1304 Trial on Omission of Regional Nodal Irradiation After Response to Neoadjuvant Chemotherapy

Olga Kantor, Ashley A. Woodfin, Michelle Connolly Specht, Society of Surgical Oncology Breast Disease Site Working Group et autres

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Oncological outcomes with and without axillary lymph node dissection in patients with residual micrometastases after neoadjuvant chemotherapy (OPBC-07/microNAC): an international, retrospective cohort study

Giacomo Montagna, Michael Alvarado, Sara Myers, Mary M Mrdutt et autres

BACKGROUND: Despite the paucity of outcome data, axillary lymph node dissection (ALND) is increasingly being omitted in patients with positive sentinel lymph nodes after neoadjuvant chemotherapy, particularly in those with low-volume residual disease. We investigated oncological outcomes in patients with breast cancer …

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Data from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

AbstractBackground: Social adversity from neighborhood disadvantage (ND) is associated with shorter breast cancer survival. Although studies have identified associations between ND and DNA methylation (DNAme) or gene expression (mRNA), a study integrating DNAme and mRNA to understand how the epigenome regulates key …

Supplementary Methods from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Methods - Survey

Supplementary Table S4 from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Table S4: Correlation results

Supplementary Table S1 from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Table S1: Differentially methylated pathways.

Supplementary Table S3 from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Table S3: Differentially expressed small non-coding RNAs.

Supplementary Figure S1 from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Figure S1: Blood cytokine levels in ADI-High Compared to ADI-Low Patients

Supplementary Figure S4 from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Figure S4: Architectural Parameters of Genes

Supplementary Figure S2 from Molecular Portraits of Social Adversity in Breast Cancer: Neighborhood Disadvantage Is Associated with Epigenetic Deregulation of Key Oncogenic Pathways

Aristeidis G. Telonis, Alexandra E Hernandez, Peter A. Borowsky, Eantiago Hernández et autres

Supplementary Figure S2: Heatmap of Perceived Disadvantage and ADI