Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
E-cadherin expression in PyMT tumors with deleted (KO) and overexpressed Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
E-cadherin expression in PyMT tumors with deleted (KO) and overexpressed Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Size (Fig. S1) and expression of Lox family members in PyMT tumors (Fig. S2) with deregulated Loxl2. Fig. S3: Loxl2 expression in PyMT tumors compared to normal mammary gland.
Accès ouvert
2023
supplementary-materials
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Suppplementary Material and Methods and related references
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Abstract The lysyl oxidase–like protein LOXL2 has been suggested to contribute to tumor progression and metastasis, but in vivo evidence has been lacking. Here we provide functional evidence that LOXL2 is a key driver of breast cancer metastasis in two conditional transgenic …
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Orthotopic injection of PyMT cells with Loxl2 overexpression (Fig. S8) and fibrillar collagen in xenografts from PyMT cells with deregulated Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Lung metastatis burden (Fig. S4) and CTCs content (Fig. S5) in 14-weeks PyMT mice with deregulated Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Primers used for genotyping (Table S1) and RT-PCR (Table S2), and list of antibodies (Table S3)
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Orthotopic injection of PyMT cells with Loxl2 overexpression (Fig. S8) and fibrillar collagen in xenografts from PyMT cells with deregulated Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Collagen organization in metastatic lungs (Fig. S6) and Tenascin-C and fibronectin expression in primary tumors and lungs from PyMT mice with deregulated Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Lung metastatis burden (Fig. S4) and CTCs content (Fig. S5) in 14-weeks PyMT mice with deregulated Loxl2
Accès ouvert
2023
other
OpenAlex
Fernando Salvador, Alberto Martín, Celia López‐Menéndez, Gema Moreno‐Bueno et autres
Abstract The lysyl oxidase–like protein LOXL2 has been suggested to contribute to tumor progression and metastasis, but in vivo evidence has been lacking. Here we provide functional evidence that LOXL2 is a key driver of breast cancer metastasis in two conditional transgenic …