Kaiyong Liu

Dichotomous associations of circulating short-chain organic acids with cognitive impairment in older adults: An epidemiological and network analysis study

Shuai Zhang, Kequn Tao, Luolin Zhou, Sheng Wang et autres

BackgroundShort-chain organic acids (SCOAs) may have paradoxical effects on neurocognition, acting as either neuroprotective bioenergetic substrates or potential neurotoxicants. However, the joint effects of SCOA mixtures on cognitive impairment and the mechanisms underlying their divergent associations remain unclear.ObjectiveTo investigate the joint effects …

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Joint effects of contaminants of emerging concern (CECs) on sleep quality in Chinese elderly: A Bayesian kernel machine regression and quantile g-computation analysis

Yuanyuan Xu, Man Cao, Yutong Zhao, H. J. Yang et autres

Despite their trace concentrations in the environment, contaminants of emerging concern (CECs) pose potential risks to human health, particularly for vulnerable populations like the elderly. However, current research provides limited insight into the relationship between CECs and sleep quality in older adults. …

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Dual CRISPR/Cas-driven amplification-free surface-enhanced Raman scattering biosensor combined with a smartphone for simultaneous detection of total and live target bacteria

Ruibao Jiao, Qun Ni, Ruirui Zhao, Xiaofan Zhu et autres

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Associations between prenatal antibiotics exposure and preschoolers’ attention-deficit hyperactivity disorder symptom trajectories: Unveiling the potential intervention strategies

Peng Ding, Baolin Wang, Juan Tong, Hui Gao et autres

BACKGROUND: Understanding the effects of prenatal antibiotic exposure on the developmental trajectories of attention-deficit hyperactivity disorder (ADHD) in offspring and exploring intervention strategies are key to managing early-life health. METHODS: This research included 2387 motherchild pairs. Antibiotics were detected in maternal urine …

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PPCPs in the Chaohu Lake Basin: Water-urine linkage and health risks for aging populations

Hao Yang, Ying Liu, Panzhu Qin, Sheng Wang et autres

The escalating consumption of pharmaceuticals and personal care products (PPCPs) has driven their continuous release into the environment, urgently warranting a comprehensive investigation of aquatic contamination profiles and risks to aquatic ecosystems and humans. This study presents a basin-wide assessment of PPCP …

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Underlying mechanisms of PPCPs on sleep disorders in the elderly: An integrated epidemiology and network toxicology study

Shuai Zhang, Kequn Tao, Li Gao, Xu Liu et autres

This study aims to investigate the association between urinary exposure to emerging contaminants, pharmaceuticals and personal care products (PPCPs), and sleep disorders, while concurrently delineating the underlying mechanism. Levels of PPCPs were biomonitored in urine samples from 3,096 older adults. Logistic quantile …

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Water consumption contributes to maternal PFAS exposure: From source to metabolic perturbations

Wei Chang, Yong-Wei Xiong, Jian Sun, Lanlan Wu et autres

Per- and polyfluoroalkyl substances (PFAS) are widespread persistent pollutants and pose a risk to human health. However, the transfer efficiencies (TEs) of PFAS from source water into maternal serum, and its metabolic pathways linking PFAS exposure and human disease are remain unclear. …

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Antibiotic resistance genes in multi-matrices of Chaohu Lake: Spatiotemporal variation and correlation with pesticides and PPCPs

Hao Yang, Hongwei Fu, Yutong Zhao, Run Li et autres

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Corrigendum to “Development of a universal one-pot CRISPR assay based on multifunctional tagged primer eliminating unstable crRNA input and PAM dependency for point-of-care detection of bacterial infections” [Biosens. Bioelectron. 287 (2025) 117718]

Xiaofan Zhu, J. B. Jiao, Qing‐Ling Ni, Yao Li et autres

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Development of a universal one-pot CRISPR assay based on multifunctional tagged primer eliminating unstable crRNA input and PAM dependency for point-of-care detection of bacterial infections

Xiaofan Zhu, J. B. Jiao, Qiang Ni, Yao Li et autres

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Body burden and health risk of pharmaceuticals in elderly population: A multi-site biomonitoring study in China

Fangting Hu, Yi Liu, Xiaoting Liu, Sheng Wang et autres

Evidence suggests that pharmaceuticals (PhACs) are widespread in the environment and may pose a threat to human health. However, limited health risk assessments are available for PhAC exposure in large and multi-site populations, especially among vulnerable populations. To address this gap, we …

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Risk prioritization and experimental validation of per- and polyfluoroalkyl substances (PFAS) in Chaohu Lake: Based on nontarget and target analyses

Wei Chang, Shendong Xu, Ting Liu, Lanlan Wu et autres

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