Accès ouvert
2026
article
OpenAlex
Philip S Nash, Gareth Ambler, Jonathan G. Best, Duncan Wilson et autres
Background And Objectives Enlarged perivascular spaces (EPVSs) in the basal ganglia (BG-EPVS) are an important marker of cerebral small vessel disease (cSVD), and EPVS in the centrum semiovale (CSO-EPVS) are part of the diagnostic criteria for cerebral amyloid angiopathy. We aimed to …
at
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Accès ouvert
2026
article
OpenAlex
Philip S. Nash, Gareth Ambler, Jonathan G. Best, Duncan Wilson et autres
BACKGROUND AND OBJECTIVES: Enlarged perivascular spaces (EPVSs) in the basal ganglia (BG-EPVS) are an important marker of cerebral small vessel disease (cSVD), and EPVS in the centrum semiovale (CSO-EPVS) are part of the diagnostic criteria for cerebral amyloid angiopathy. We aimed to …
gb, cn, pl, dk, ch, nl, de, au, kr, jp, tr, ag, us, hk
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Accès ouvert
2026
article
OpenAlex
Philip S Nash, Gareth Ambler, Jonathan G. Best, Duncan Wilson et autres
INTRODUCTION: Glomerular hyperfiltration has previously been associated with cardiovascular events and mortality but has scarcely been investigated in patients with stroke. PATIENTS AND METHODS: We used pooled data from an individual patient data meta-analysis of prospective, cohort studies of stroke or TIA …
gb, cn, pl, dk, at, jp, ch, nl, de, au, kr, tr, ag, il, ca, hk
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Accès ouvert
2026
article
OpenAlex
Philip S Nash, Gareth Ambler, Jonathan G. Best, Duncan Wilson et autres
Introduction Glomerular hyperfiltration has previously been associated with cardiovascular events and mortality but has scarcely been investigated in patients with stroke. Patients And Methods We used pooled data from an individual patient data meta-analysis of prospective, cohort studies of stroke or TIA …
at
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Accès ouvert
2025
article
OpenAlex
Stefan T. Engelter, Josefin E. Kaufmann, Annaelle Zietz, Andreas R. Luft et autres
Importance: Levodopa enhances dopaminergic signaling and may stimulate neuroplasticity, which could potentially enhance motor recovery after stroke. Levodopa is used in stroke rehabilitation despite mixed evidence for its effectiveness. Objective: To determine whether levodopa compared with placebo, administered in addition to standardized …
ch, us, au, gb
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Accès ouvert
2025
article
OpenAlex
Jeremy Molad, Kaori Miwa, Philip S. Nash, Gareth Ambler et autres
Background Patients with chronic kidney disease are at increased risk of stroke and frequently have cerebral microbleeds. Whether such patients also encounter an increased risk of recurrent stroke has not been firmly established. We aimed to determine whether impaired kidney function is …
il, jp, gb, at, ch, us, nl, de, au, kr, tr, ag, ca, hk, cn
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Accès ouvert
2024
article
OpenAlex
Simon Fandler‐Höfler, Sebastian Eppinger, Gareth Ambler, Philip S. Nash et autres
Importance: Cerebral small vessel disease (SVD) is associated with various cerebrovascular outcomes, but data on sex differences in SVD are scarce. Objective: To investigate whether the frequency, severity, and distribution of cerebral microbleeds (CMB), other SVD markers on magnetic resonance imaging (MRI), …
at, gb, kr, jp, fr, de, hk, es, us, be, tr, il, ca, ch, nl, dk, au, cn, ie, sg
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Accès ouvert
2024
article
OpenAlex
Tolga Dittrich, Anh Nguyên, Peter B. Sporns, Anna Toebak et autres
INTRODUCTION: Automated CT perfusion (aCTP) is commonly used to select patients with anterior circulation large vessel occlusion (aLVO) for endovascular treatment (EVT). The equivalence of visually assessed Non-contrast CT Alberta Stroke Program Early CT Scores (ASPECTS) and aCTP based selection in predicting …
ch
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Accès ouvert
2024
article
OpenAlex
Lina Sojak, Anna Toebak, Camilla Gallino, Tennessee von Streng et autres
INTRODUCTION: There is limited understanding of the pathomechanistic relationship between leptomeningeal collateral formation and ischaemic stroke aetiology. We aimed to assess the association of leptomeningeal collateral status and ischaemic stroke aetiology, using the widely recognised "Trial of Org 10172 in Acute Stroke …
ch, jp
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Accès ouvert
2024
article
OpenAlex
Josefin E. Kaufmann, Eric L. Harshfield, Henrik Gensicke, Susanne Wegener et autres
Importance: Cervical artery dissection is the most common cause of stroke in younger adults. To date, there is no conclusive evidence on which antithrombotic therapy should be used to treat patients. Objective: To perform an individual patient data meta-analysis of randomized clinical …
ch, gb, de, dk, au
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Accès ouvert
2024
article
OpenAlex
Tolga Dittrich, Tennessee von Streng, Anna Toebak, Annaelle Zietz et autres
INTRODUCTION: The impact of leptomeningeal collateralization on the efficacy of mechanical thrombectomy (MT) in patients with anterior circulation large vessel occlusion (aLVO) presenting in the 6-24 h time window remains poorly elucidated. PATIENTS AND METHODS: Retrospective multicenter study of aLVO patients presenting …
ch
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Accès ouvert
2023
article
OpenAlex
Mohamed Kassem, Soraya S. de Kam, Twan J. van Velzen, Rob J. van der Geest et autres
PURPOSE: Carotid intraplaque hemorrhage (IPH) on MRI predicts stroke. Magnetization-prepared rapid acquisition gradient (MP-RAGE) is widely used to detect IPH. CE-MRA is used routinely to assess stenosis. Initial studies indicated that IPH can be identified on mask images of CE-MRA, while Time-of-Flight …
nl, ch, gb, it
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