Itzhak Fried

Safety and adverse event profiles in neuromodulation therapies for drug-resistant epilepsy

Yuta Tanoue, Masaki Izumi, Samuel S. Ahn, Dawn S. Eliashiv et autres

Drug-resistant epilepsy (DRE) is associated with clinical and psychosocial burdens, and non-pharmacological therapies play an important role when seizure control cannot be achieved with antiseizure medications alone. Neuromodulation therapies, including vagus nerve stimulation (VNS), deep brain stimulation (DBS), and responsive neurostimulation (RNS), …

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Event Segmentation Patterns of Real-World Navigation from a First-Person Perspective

Sydney Josifek, Luis Garcia, Uros Topalovic, Mauricio Vallejo Martelo et autres

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Incidental visual attention and subsequent memory for landmarks during real-world navigation

Lensky Augustin, Alireza Kazemi, Luis Garcia, Uros Topalovic et autres

us, dk, fr, no (code pays fourni par la source)

Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy

Dawn Eliashiv, Vikram R. Rao, Barbara C. Jobst, Jerzy P. Szaflarski et autres

BACKGROUND AND OBJECTIVES: Neuromodulation therapies are approved for the treatment of focal epilepsy based on data from randomized controlled trials (RCTs). After approval of a responsive direct brain stimulation device (The RNS System for focal epilepsy), the Food and Drug Administration required …

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Eye movements reflect memory-related theta activity in the human brain

Humza N. Zubair, Matthias Stangl, Uros Topalovic, Cory S. Inman et autres

Numerous studies across species emphasize the importance of theta oscillations within medial temporal lobe (MTL) regions, such as the hippocampus, in relation to memory. In rodents, physical movement strongly influences theta activity, while this relationship remains more ambiguous in primates. This disparity …

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Multi-branch convolutional neural network and intracranial EEG high-frequency oscillations predict post-surgical seizure outcomes

Madhumathi Devaraj, Yihe Chen, Shuang Wang, Michael R. Sperling et autres

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Multi-branch convolutional neural network using intracranial EEG high frequency oscillation features for predicting post-surgical seizure outcomes

Yihe Chen, Shuang Wang, Michael R. Sperling, Noa Herz et autres

Abstract Pathological high-frequency oscillations (HFOs 80-600 Hz) in intracranial EEG distinguish epileptogenic cortex. However, it is uncertain whether utilizing HFO measures for surgical planning improve epilepsy surgery seizure outcomes and minimize morbidity. The clinical gold standard for planning an epilepsy surgery involves …

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Reading specific memories from human neurons before and after sleep

Yuanyi Ding, Soraya L. S. Dunn, John J. Sakon, Yipeng Zhang et autres

The ability to retrieve a single episode encountered just once is a hallmark of human intelligence and episodic memory[1]. Yet, decoding a specific memory from neuronal activity in the human brain remains a formidable challenge. Here, we develop a transformer neural network …

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Algorithmic representations in the human brain that underlie schema generalisation

Cognitive Science Society 2025, Adrish Anand, Habiba Azab, Jacob Bakermans et autres

The human brain represents structure in the external world as “cognitive maps”. However, it remains unknown how it represents structure in one’s own behaviour. Recent findings show rodent medial-prefrontal cortex (mPFC) does this with a structure-sensitive representation, where all future actions are …

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Publisher Correction: Human neural dynamics of real-world and imagined navigation

Martin Seeber, Matthias Stangl, Mauricio Vallejo Martelo, Uros Topalovic et autres

In the version of the article initially published, Fig. 3c was identical to Fig. 3a and has now been amended with the correct data in the HTML and PDF versions of the article.

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Human neural dynamics of real-world and imagined navigation

Martin Seeber, Matthias Stangl, Mauricio Vallejo Martelo, Uros Topalovic et autres

The ability to form episodic memories and later imagine them is integral to the human experience, influencing our recollection of the past and envisioning of the future. While rodent studies suggest the medial temporal lobe, especially the hippocampus, is involved in these …

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Modality-Specific and Amodal Language Processing by Single Neurons

Yair Lakretz, Naama Friedmann, Jean-Rémi King, Emily A. Mankin et autres

fr, il, us (code pays fourni par la source)