Ian Rees

A scoping review of social work with Roma and Traveller communities: introducing the ROMA model

Dan Allen, J. W. Bolton, Allison Hulmes, Mairtain Moloney-Neachtain et autres

Although The Strasbourg Declaration on Roma presents a list of priorities that aim to address the social and economic marginalisation of Roma and Traveller people in Europe, the contribution that social work is making to efforts to achieve these aims is unclear. …

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Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls

Carla Fiorella Murillo Perez, Holly Fisher, Shaun Hiu, Dorcas Kareithi et autres

BACKGROUND & AIMS: The Primary Biliary Cholangitis (PBC) Obeticholic Acid (OCA) International Study of Efficacy (POISE) randomized, double-blind, placebo-controlled trial demonstrated that OCA reduced biomarkers associated with adverse clinical outcomes (ie, alkaline phosphatase, bilirubin, aspartate aminotransferase, and alanine aminotransferase) in patients with …

ca, gb, us, nl, it, be, de, es, gr, at, fr (code pays fourni par la source)

Science-Based Assessment of Source Materials for Cell-Based Medicines: Report of a Stakeholders Workshop

Peter W. Andrews, Curtis O. Asante, Ivana Barbaric, Louise Bisset et autres

Human pluripotent stem cells (hPSCs) have the potential to transform medicine. However, hurdles remain to ensure safety for such cellular products. Science-based understanding of the requirements for source materials is required as are appropriate materials. Leaders in hPSC biology, clinical translation, biomanufacturing …

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Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

Marco Carbone, Alessandra Nardi, Steve Flack, Guido Carpino et autres

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Determining neutrino oscillation parameters from atmospheric muon neutrino disappearance with three years of IceCube DeepCore data

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar et autres

We present a measurement of neutrino oscillations via atmospheric muon neutrino disappearance with three years of data of the completed IceCube neutrino detector. DeepCore, a region of denser IceCube instrumentation, enables the detection and reconstruction of atmospheric muon neutrinos between 10 and …

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Development of a general analysis and unfolding scheme and its application to measure the energy spectrum of atmospheric neutrinos with IceCube

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar et autres

We present the development and application of a generic analysis scheme for the measurement of neutrino spectra with the IceCube detector. This scheme is based on regularized unfolding, preceded by an event selection which uses a Minimum Redundancy Maximum Relevance algorithm to …

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Atmospheric and astrophysical neutrinos above 1 TeV interacting in IceCube

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar et autres

The IceCube Neutrino Observatory was designed primarily to search for high-energy (TeV-PeV) neutrinos produced in distant astrophysical objects. A search for $\ensuremath{\gtrsim}100\text{ }\text{ }\mathrm{TeV}$ neutrinos interacting inside the instrumented volume has recently provided evidence for an isotropic flux of such neutrinos. At …

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Multipole analysis of IceCube data to search for dark matter accumulated in the Galactic halo

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar et autres

Dark matter which is bound in the Galactic halo might self-annihilate and produce a flux of stable final state particles, e.g. high energy neutrinos. These neutrinos can be detected with IceCube, a cubic-kilometer sized Cherenkov detector. Given IceCube’s large field of view, …

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SEARCH FOR PROMPT NEUTRINO EMISSION FROM GAMMA-RAY BURSTS WITH ICECUBE

M. G. Aartsen, M. Ackermann, J. Auffenberg, P. Hallen et autres

We present constraints derived from a search of four years of IceCube data for a prompt neutrino flux from gamma-ray bursts (GRBs). A single low-significance neutrino, compatible with the atmospheric neutrino background, was found in coincidence with one of the 506 observed …

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IceCube-Gen2: A Vision for the Future of Neutrino Astronomy in Antarctica

Gen Collaboration, M. G. Aartsen, M. Ackermann, J. Adams et autres

The recent observation by the IceCube neutrino observatory of an astrophysical flux of neutrinos represents the "first light" in the nascent field of neutrino astronomy. The observed diffuse neutrino flux seems to suggest a much larger level of hadronic activity in the …

Multimessenger search for sources of gravitational waves and high-energy neutrinos: Initial results for LIGO-Virgo and IceCube

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar et autres

We report the results of a multimessenger search for coincident signals from the LIGO and Virgo gravitational-wave observatories and the partially completed IceCube high-energy neutrino detector, including periods of joint operation between 2007--2010. These include parts of the 2005--2007 run and the …

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SEARCHES FOR EXTENDED AND POINT-LIKE NEUTRINO SOURCES WITH FOUR YEARS OF ICECUBE DATA

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar et autres

We present results on searches for point-like sources of neutrinos using four years of IceCube data, including the first year of data from the completed 86 string detector. The total livetime of the combined data set is 1373 days. For an E …

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