Victor J Avalos Herrera

Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a model-based cost-effectiveness analysis of a pragmatic, cluster-randomised trial in seven low-income and middle-income countries

Mwayi Kachapila, Raymond Oppong, Adesoji Ademuyiwa, Aneel Bhangu et autres

BACKGROUND: Surgical site infection (SSI) is a major burden on patients and health systems. This study assessed the cost-effectiveness of routine change of sterile gloves and instruments before abdominal wall closure to prevent SSI. METHODS: A decision-analytic model was built to estimate …

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Strategies to minimise and monitor biases and imbalances by arm in surgical cluster randomised trials: evidence from ChEETAh, a trial in seven low- and middle-income countries

Didier Ahogni, Aristide Ahounou, K. Alassan Boukari, Oswald Gbéhadé et autres

BACKGROUND: Cluster randomised controlled trials (cRCT) present challenges regarding risks of bias and chance imbalances by arm. This paper reports strategies to minimise and monitor biases and imbalances in the ChEETAh cRCT. METHODS: ChEETAh was an international cRCT (hospitals as clusters) evaluating …

Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries

Aaron B Andoh, Abantanga Atindaana Francis, Abdulhafiz A Abdulkarim, Abdulhafiz Adesunkanmi et autres

BACKGROUND: Surgical site infection (SSI) remains the most common complication of surgery around the world. WHO does not make recommendations for changing gloves and instruments before wound closure owing to a lack of evidence. This study aimed to test whether a routine …