C.S Rabkin

CD4/CD8 Ratio and Cancer Risk among Adults with HIV

A.M Mayor, S.B Coburn, Dorothy J. Wiley, M.M Kitahata et autres

Background: Independent of CD4 cell count, a low CD4/CD8 ratio in people with HIV (PWH) is associated with deleterious immune senescence, activation, and inflammation, which may contribute to carcinogenesis and excess cancer risk. We examined whether low CD4/CD8 ratios predicted cancer among …

us (code pays fourni par la source)

Comparative outcomes for mature T-cell and NK/T-cell lymphomas in people with and without HIV and to AIDS-defining lymphomas

Edward R. Cachay, M.J Silverberg, Jessica L. Castilho, Marta Epeldegui et autres

There are no studies comparing the prognosis for mature T-cell lymphoma (TCL) in people with HIV (PWH) to people without HIV (PWoH) and to AIDS-defining B-cell lymphomas (A-BCLs) in the modern antiretroviral therapy era. North American AIDS Cohort Collaboration on Research and …

us (code pays fourni par la source)

Secular Trends in Breast Cancer Risk Among Women With HIV Initiating ART in North America

A.M Mayor, R.D Moore, Trinity Sterling, Jian Li et autres

Background: Studies suggest lower risk of breast cancer in women with HIV versus without HIV. These estimates may be biased by lower life expectancy and younger age distribution of women with HIV. Our analysis evaluated this bias and characterized secular trends in …

us (code pays fourni par la source)

Association of Immunosuppression and Human Immunodeficiency Virus (HIV) Viremia with Anal Cancer Risk in Persons Living with HIV in the United States and Canada

A. Kroch, C.A. Benson, R.F. Hunter-Mellado, J. Jing et autres

Background: People living with human immunodeficiency virus (HIV; PLWH) have a markedly elevated anal cancer risk, largely due to loss of immunoregulatory control of oncogenic human papillomavirus infection. To better understand anal cancer development and prevention, we determined whether recent, past, cumulative, …

Contributions of traditional and HIV-related risk factors on non-AIDS-defining cancer, myocardial infarction, and end-stage liver and renal diseases in adults with HIV in the USA and Canada: a collaboration of cohort studies

C. Wong, F.J. Palella, K. Anastos, C.M. Boyd et autres

us (code pays fourni par la source)